D278-0479 Screening compound: 2-hydroxy-5-[(2-methyl-6-phenylpyrimidin-4-yl)amino]benzoic acid

D278-0479 Screening compound: 2-hydroxy-5-[(2-methyl-6-phenylpyrimidin-4-yl)amino]benzoic acid
D278-0479 Screening compound: 2-hydroxy-5-[(2-methyl-6-phenylpyrimidin-4-yl)amino]benzoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0479
2-hydroxy-5-[(2-methyl-6-phenylpyrimidin-4-yl)amino]benzoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0479

Molecular Formula

C18H15N3O3 (C18 H15 N3 O3)

Compound Name

2-hydroxy-5-[(2-methyl-6-phenylpyrimidin-4-yl)amino]benzoic acid

IUPAC name

2-hydroxy-5-[(2-methyl-6-phenylpyrimidin-4-yl)amino]benzoic acid

SMILES

Cc1nc(-c2ccccc2)cc(Nc(cc2)cc(C(O)=O)c2O)n1

InChI

InChI=1S/C18H15N3O3/c1-11-19-15(12-5-3-2-4-6-12)10-17(20-11)21-13-7-8-16(22)14(9-13)18(23)24/h2-10,22H,1H3,(H,23,24)(H,19,20,21)

InChI Key

YXNWPXCFUDPOME-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09982355

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

321.34

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.885

Distribution Coefficient, logD

4.885

Water Solubility, LogSw

-4.24

Polar Surface Area

72.587

Acid Dissociation Constant (pKa)

3.47

Base Dissociation Constant (pKb)

7.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

D278-0479 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Nuclear receptors

References: we are preparing a list of scientific research reports with D278-0479 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0479?
Check Price and Availability of D278-0479, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D278-0479 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0479
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0479
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0479 available by request