D278-0487 Screening compound: 4-(ethanesulfonyl)-2-[(6-phenylpyrimidin-4-yl)amino]phenol

D278-0487 Screening compound: 4-(ethanesulfonyl)-2-[(6-phenylpyrimidin-4-yl)amino]phenol
D278-0487 Screening compound: 4-(ethanesulfonyl)-2-[(6-phenylpyrimidin-4-yl)amino]phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0487
4-(ethanesulfonyl)-2-[(6-phenylpyrimidin-4-yl)amino]phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0487

Molecular Formula

C18H17N3O3S (C18 H17 N3 O3 S)

Compound Name

4-(ethanesulfonyl)-2-[(6-phenylpyrimidin-4-yl)amino]phenol

IUPAC name

4-(ethanesulfonyl)-2-[(6-phenylpyrimidin-4-yl)amino]phenol

SMILES

CCS(c(cc1)cc(Nc2ncnc(-c3ccccc3)c2)c1O)(=O)=O

InChI

InChI=1S/C18H17N3O3S/c1-2-25(23,24)14-8-9-17(22)16(10-14)21-18-11-15(19-12-20-18)13-6-4-3-5-7-13/h3-12,22H,2H2,1H3,(H,19,20,21)

InChI Key

SRRIGRNGJWRHTC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD26967652

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

355.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.254

Distribution Coefficient, logD

3.040

Water Solubility, LogSw

-3.46

Polar Surface Area

74.143

Acid Dissociation Constant (pKa)

7.90

Base Dissociation Constant (pKb)

6.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

D278-0487 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-Aging Library (44940 compounds)

Nucleoside Mimetics Library (2197 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Cancer
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Structure:
  • Mimetics
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D278-0487 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0487?
Check Price and Availability of D278-0487, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D278-0487 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0487
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0487
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0487 available by request