D278-0579 Screening compound: 4-[(2,6-dimethylpyrimidin-4-yl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide

D278-0579 Screening compound: 4-[(2,6-dimethylpyrimidin-4-yl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide
D278-0579 Screening compound: 4-[(2,6-dimethylpyrimidin-4-yl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0579
4-[(2,6-dimethylpyrimidin-4-yl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0579

Molecular Formula

C17H17N5O2S (C17 H17 N5 O2 S)

Compound Name

4-[(2,6-dimethylpyrimidin-4-yl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide

IUPAC name

4-[(26-dimethylpyrimidin-4-yl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide

SMILES

Cc1cc(Nc(cc2)ccc2S(Nc2ncccc2)(=O)=O)nc(C)n1

InChI

InChI=1S/C17H17N5O2S/c1-12-11-17(20-13(2)19-12)21-14-6-8-15(9-7-14)25(23,24)22-16-5-3-4-10-18-16/h3-11H,1-2H3,(H,18,22)(H,19,20,21)

InChI Key

ZAPPMRLVWNLOIQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10480079

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

355.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.351

Distribution Coefficient, logD

1.846

Water Solubility, LogSw

-2.85

Polar Surface Area

77.973

Acid Dissociation Constant (pKa)

7.77

Base Dissociation Constant (pKb)

7.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.80

D278-0579 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Agro:
  • Agro
  • Agro
Targets:
  • Kinases
  • Ion Channels
  • Kinases

References: we are preparing a list of scientific research reports with D278-0579 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0579?
Check Price and Availability of D278-0579, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D278-0579 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0579
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0579
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0579 available by request