D278-0857 Screening compound: 2-({5,9-dimethyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl}sulfanyl)-1-(morpholin-4-yl)ethan-1-one

D278-0857 Screening compound: 2-({5,9-dimethyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl}sulfanyl)-1-(morpholin-4-yl)ethan-1-one
D278-0857 Screening compound: 2-({5,9-dimethyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl}sulfanyl)-1-(morpholin-4-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-0857
2-({5,9-dimethyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl}sulfanyl)-1-(morpholin-4-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-0857

Molecular Formula

C18H20N4O2S (C18 H20 N4 O2 S)

Compound Name

2-({5,9-dimethyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl}sulfanyl)-1-(morpholin-4-yl)ethan-1-one

IUPAC name

2-({59-dimethyl-[124]triazolo[43-a]quinolin-1-yl}sulfanyl)-1-(morpholin-4-yl)ethan-1-one

SMILES

Cc1cccc2c1n1c(SCC(N3CCOCC3)=O)nnc1cc2C

InChI

InChI=1S/C18H20N4O2S/c1-12-4-3-5-14-13(2)10-15-19-20-18(22(15)17(12)14)25-11-16(23)21-6-8-24-9-7-21/h3-5,10H,6-9,11H2,1-2H3

InChI Key

WUUPHGQZQXWNIV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09057294

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.533

Distribution Coefficient, logD

2.533

Water Solubility, LogSw

-2.73

Polar Surface Area

45.159

Acid Dissociation Constant (pKa)

19.58

Base Dissociation Constant (pKb)

1.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

D278-0857 in Drug Discovery

Included in Screening Libraries

Immunological Library (6760 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with D278-0857 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-0857?
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What is the minimum amount of D278-0857 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-0857
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-0857
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-0857 available by request