D278-1225 Screening compound: 2-({[1,2,4]triazolo[4,3-a]quinolin-1-ylsulfanyl}methyl)benzonitrile

D278-1225 Screening compound: 2-({[1,2,4]triazolo[4,3-a]quinolin-1-ylsulfanyl}methyl)benzonitrile
D278-1225 Screening compound: 2-({[1,2,4]triazolo[4,3-a]quinolin-1-ylsulfanyl}methyl)benzonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound D278-1225
2-({[1,2,4]triazolo[4,3-a]quinolin-1-ylsulfanyl}methyl)benzonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D278-1225

Molecular Formula

C18H12N4S (C18 H12 N4 S)

Compound Name

2-({[1,2,4]triazolo[4,3-a]quinolin-1-ylsulfanyl}methyl)benzonitrile

IUPAC name

2-({[124]triazolo[43-a]quinolin-1-ylsulfanyl}methyl)benzonitrile

SMILES

N#Cc1c(CSc2nnc3n2c(cccc2)c2cc3)cccc1

InChI

InChI=1S/C18H12N4S/c19-11-14-6-1-2-7-15(14)12-23-18-21-20-17-10-9-13-5-3-4-8-16(13)22(17)18/h1-10H,12H2

InChI Key

GWLWDUZAWRBMNS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06488543

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

316.39

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.860

Distribution Coefficient, logD

3.860

Water Solubility, LogSw

-4.30

Polar Surface Area

38.138

Acid Dissociation Constant (pKa)

23.75

Base Dissociation Constant (pKb)

2.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

D278-1225 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Antiparasite Library (23996 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Infections
  • Immune system
  • animal
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Agro:
  • Agro
  • Agro
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D278-1225 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D278-1225?
Check Price and Availability of D278-1225, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D278-1225 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D278-1225
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D278-1225
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D278-1225 available by request