D282-0123 Screening compound: N-[(1H-1,3-benzodiazol-2-yl)methyl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide

D282-0123 Screening compound: N-[(1H-1,3-benzodiazol-2-yl)methyl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide
D282-0123 Screening compound: N-[(1H-1,3-benzodiazol-2-yl)methyl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D282-0123
N-[(1H-1,3-benzodiazol-2-yl)methyl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D282-0123

Molecular Formula

C19H16N4OS (C19 H16 N4 OS)

Compound Name

N-[(1H-1,3-benzodiazol-2-yl)methyl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide

IUPAC name

N-[(1H-13-benzodiazol-2-yl)methyl]-4-methyl-2-phenyl-13-thiazole-5-carboxamide

SMILES

Cc1c(C(NCc2nc(cccc3)c3[nH]2)=O)sc(-c2ccccc2)n1

InChI

InChI=1S/C19H16N4OS/c1-12-17(25-19(21-12)13-7-3-2-4-8-13)18(24)20-11-16-22-14-9-5-6-10-15(14)23-16/h2-10H,11H2,1H3,(H,20,24)(H,22,23)

InChI Key

YCURKYAZDLYJKA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08568366

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

348.43

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.050

Distribution Coefficient, logD

4.050

Water Solubility, LogSw

-4.14

Polar Surface Area

55.244

Acid Dissociation Constant (pKa)

11.44

Base Dissociation Constant (pKb)

4.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

D282-0123 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Antibacterial Compounds Library (13827 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Others
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D282-0123 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D282-0123?
Check Price and Availability of D282-0123, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D282-0123 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D282-0123
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D282-0123
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D282-0123 available by request