D282-0137 Screening compound: ethyl 4,5-dimethyl-2-(4-methyl-2-phenyl-1,3-thiazole-5-amido)thiophene-3-carboxylate

D282-0137 Screening compound: ethyl 4,5-dimethyl-2-(4-methyl-2-phenyl-1,3-thiazole-5-amido)thiophene-3-carboxylate
D282-0137 Screening compound: ethyl 4,5-dimethyl-2-(4-methyl-2-phenyl-1,3-thiazole-5-amido)thiophene-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound D282-0137
ethyl 4,5-dimethyl-2-(4-methyl-2-phenyl-1,3-thiazole-5-amido)thiophene-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D282-0137

Molecular Formula

C20H20N2O3S2 (C20 H20 N2 O3 S2)

Compound Name

ethyl 4,5-dimethyl-2-(4-methyl-2-phenyl-1,3-thiazole-5-amido)thiophene-3-carboxylate

IUPAC name

ethyl 45-dimethyl-2-(4-methyl-2-phenyl-13-thiazole-5-amido)thiophene-3-carboxylate

SMILES

CCOC(c1c(NC(c2c(C)nc(-c3ccccc3)s2)=O)sc(C)c1C)=O

InChI

InChI=1S/C20H20N2O3S2/c1-5-25-20(24)15-11(2)13(4)26-19(15)22-17(23)16-12(3)21-18(27-16)14-9-7-6-8-10-14/h6-10H,5H2,1-4H3,(H,22,23)

InChI Key

DYKHHFBEZXBQLL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08568371

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.937

Distribution Coefficient, logD

1.528

Water Solubility, LogSw

-4.70

Polar Surface Area

54.188

Acid Dissociation Constant (pKa)

3.99

Base Dissociation Constant (pKb)

-1.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

D282-0137 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D282-0137 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D282-0137?
Check Price and Availability of D282-0137, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D282-0137 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D282-0137
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D282-0137
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D282-0137 available by request