D282-0147 Screening compound: N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide

D282-0147 Screening compound: N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide
D282-0147 Screening compound: N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D282-0147
N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D282-0147

Molecular Formula

C20H14BrN3OS2 (C20 H14 BrN3 OS2)

Compound Name

N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide

IUPAC name

N-[4-(4-bromophenyl)-13-thiazol-2-yl]-4-methyl-2-phenyl-13-thiazole-5-carboxamide

SMILES

Cc1c(C(Nc2nc(-c(cc3)ccc3Br)cs2)=O)sc(-c2ccccc2)n1

InChI

InChI=1S/C20H14BrN3OS2/c1-12-17(27-19(22-12)14-5-3-2-4-6-14)18(25)24-20-23-16(11-26-20)13-7-9-15(21)10-8-13/h2-11H,1H3,(H,23,24,25)

InChI Key

HUUYNIHAEGSORN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09540768

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.39

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.727

Distribution Coefficient, logD

6.727

Water Solubility, LogSw

-5.90

Polar Surface Area

43.415

Acid Dissociation Constant (pKa)

10.51

Base Dissociation Constant (pKb)

1.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.00

D282-0147 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D282-0147 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D282-0147?
Check Price and Availability of D282-0147, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D282-0147 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D282-0147
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D282-0147
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D282-0147 available by request