D282-0168 Screening compound: N-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide

D282-0168 Screening compound: N-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide
D282-0168 Screening compound: N-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D282-0168
N-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D282-0168

Molecular Formula

C22H19N3OS2 (C22 H19 N3 OS2)

Compound Name

N-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-4-methyl-2-phenyl-1,3-thiazole-5-carboxamide

IUPAC name

N-[4-(34-dimethylphenyl)-13-thiazol-2-yl]-4-methyl-2-phenyl-13-thiazole-5-carboxamide

SMILES

Cc1c(C(Nc2nc(-c3cc(C)c(C)cc3)cs2)=O)sc(-c2ccccc2)n1

InChI

InChI=1S/C22H19N3OS2/c1-13-9-10-17(11-14(13)2)18-12-27-22(24-18)25-20(26)19-15(3)23-21(28-19)16-7-5-4-6-8-16/h4-12H,1-3H3,(H,24,25,26)

InChI Key

ISWHJHDBNIYQOX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08568382

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.54

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.755

Distribution Coefficient, logD

6.755

Water Solubility, LogSw

-5.70

Polar Surface Area

43.415

Acid Dissociation Constant (pKa)

10.51

Base Dissociation Constant (pKb)

2.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

D282-0168 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D282-0168 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D282-0168?
Check Price and Availability of D282-0168, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D282-0168 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D282-0168
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D282-0168
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D282-0168 available by request