D282-0477 Screening compound: N-[4-(4-fluorophenyl)-5-methyl-1,3-thiazol-2-yl]-2-(2-phenyl-1,3-thiazol-4-yl)acetamide

D282-0477 Screening compound: N-[4-(4-fluorophenyl)-5-methyl-1,3-thiazol-2-yl]-2-(2-phenyl-1,3-thiazol-4-yl)acetamide
D282-0477 Screening compound: N-[4-(4-fluorophenyl)-5-methyl-1,3-thiazol-2-yl]-2-(2-phenyl-1,3-thiazol-4-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D282-0477
N-[4-(4-fluorophenyl)-5-methyl-1,3-thiazol-2-yl]-2-(2-phenyl-1,3-thiazol-4-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D282-0477

Molecular Formula

C21H16FN3OS2 (C21 H16 FN3 OS2)

Compound Name

N-[4-(4-fluorophenyl)-5-methyl-1,3-thiazol-2-yl]-2-(2-phenyl-1,3-thiazol-4-yl)acetamide

IUPAC name

N-[4-(4-fluorophenyl)-5-methyl-13-thiazol-2-yl]-2-(2-phenyl-13-thiazol-4-yl)acetamide

SMILES

Cc1c(-c(cc2)ccc2F)nc(NC(Cc2csc(-c3ccccc3)n2)=O)s1

InChI

InChI=1S/C21H16FN3OS2/c1-13-19(14-7-9-16(22)10-8-14)25-21(28-13)24-18(26)11-17-12-27-20(23-17)15-5-3-2-4-6-15/h2-10,12H,11H2,1H3,(H,24,25,26)

InChI Key

INZAXEWTEHMGHO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08568291

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.560

Distribution Coefficient, logD

5.559

Water Solubility, LogSw

-5.56

Polar Surface Area

43.891

Acid Dissociation Constant (pKa)

10.58

Base Dissociation Constant (pKb)

-0.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

D282-0477 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D282-0477 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D282-0477?
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What is the minimum amount of D282-0477 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D282-0477
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D282-0477
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D282-0477 available by request