D282-0479 Screening compound: 2-(2-phenyl-1,3-thiazol-4-yl)-N-[4-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-thiazol-2-yl]acetamide

D282-0479 Screening compound: 2-(2-phenyl-1,3-thiazol-4-yl)-N-[4-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-thiazol-2-yl]acetamide
D282-0479 Screening compound: 2-(2-phenyl-1,3-thiazol-4-yl)-N-[4-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-thiazol-2-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D282-0479
2-(2-phenyl-1,3-thiazol-4-yl)-N-[4-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-thiazol-2-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D282-0479

Molecular Formula

C24H21N3OS2 (C24 H21 N3 OS2)

Compound Name

2-(2-phenyl-1,3-thiazol-4-yl)-N-[4-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-thiazol-2-yl]acetamide

IUPAC name

2-(2-phenyl-13-thiazol-4-yl)-N-[4-(5678-tetrahydronaphthalen-2-yl)-13-thiazol-2-yl]acetamide

SMILES

O=C(Cc1csc(-c2ccccc2)n1)Nc1nc(-c2cc(CCCC3)c3cc2)cs1

InChI

InChI=1S/C24H21N3OS2/c28-22(13-20-14-29-23(25-20)17-7-2-1-3-8-17)27-24-26-21(15-30-24)19-11-10-16-6-4-5-9-18(16)12-19/h1-3,7-8,10-12,14-15H,4-6,9,13H2,(H,26,27,28)

InChI Key

WXHTWYKLKYUPQY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06873232

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.58

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.886

Distribution Coefficient, logD

6.886

Water Solubility, LogSw

-6.23

Polar Surface Area

43.041

Acid Dissociation Constant (pKa)

11.66

Base Dissociation Constant (pKb)

0.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

D282-0479 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Regenerative Medicine Focused Library (23016 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D282-0479 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D282-0479?
Check Price and Availability of D282-0479, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D282-0479 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D282-0479
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D282-0479
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D282-0479 available by request