D292-0062 Screening compound: 1-(4,6-dimethylpyrimidin-2-yl)-3-methyl-4-(3-methylthiophen-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one

D292-0062 Screening compound: 1-(4,6-dimethylpyrimidin-2-yl)-3-methyl-4-(3-methylthiophen-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one
D292-0062 Screening compound: 1-(4,6-dimethylpyrimidin-2-yl)-3-methyl-4-(3-methylthiophen-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D292-0062
1-(4,6-dimethylpyrimidin-2-yl)-3-methyl-4-(3-methylthiophen-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D292-0062

Molecular Formula

C18H19N5OS (C18 H19 N5 OS)

Compound Name

1-(4,6-dimethylpyrimidin-2-yl)-3-methyl-4-(3-methylthiophen-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-6-one

IUPAC name

1-(46-dimethylpyrimidin-2-yl)-3-methyl-4-(3-methylthiophen-2-yl)-1H4H5H6H7H-pyrazolo[34-b]pyridin-6-one

SMILES

Cc1c(C(CC(N2)=O)c3c2n(-c2nc(C)cc(C)n2)nc3C)scc1

InChI

InChI=1S/C18H19N5OS/c1-9-5-6-25-16(9)13-8-14(24)21-17-15(13)12(4)22-23(17)18-19-10(2)7-11(3)20-18/h5-7,13H,8H2,1-4H3,(H,21,24)/t13-/m0/s1

InChI Key

CJOVUUHDSPTEOM-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD18487852

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

353.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.553

Distribution Coefficient, logD

2.477

Water Solubility, LogSw

-2.89

Polar Surface Area

57.221

Acid Dissociation Constant (pKa)

12.12

Base Dissociation Constant (pKb)

6.68

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

D292-0062 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

KRAS-Targeted Library (16000 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D292-0062 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D292-0062?
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What is the minimum amount of D292-0062 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D292-0062
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D292-0062
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D292-0062 available by request