D294-0768 Screening compound: N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-2-fluorobenzamide

D294-0768 Screening compound: N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-2-fluorobenzamide
D294-0768 Screening compound: N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-2-fluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D294-0768
N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-2-fluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D294-0768

Molecular Formula

C19H14ClFN4O2S (C19 H14 ClFN4 O2 S)

Compound Name

N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-2-fluorobenzamide

IUPAC name

N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-134-thiadiazol-2-yl}-2-fluorobenzamide

SMILES

O=C(c(cccc1)c1F)Nc1nnc(C(CC2=O)CN2c(cc2)ccc2Cl)s1

InChI

InChI=1S/C19H14ClFN4O2S/c20-12-5-7-13(8-6-12)25-10-11(9-16(25)26)18-23-24-19(28-18)22-17(27)14-3-1-2-4-15(14)21/h1-8,11H,9-10H2,(H,22,24,27)/t11-/m1/s1

InChI Key

UENQXNGSPIOVJB-LLVKDONJSA-N

MDL Number (MFCD)

MFCD09270547

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.86

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.748

Distribution Coefficient, logD

1.903

Water Solubility, LogSw

-4.57

Polar Surface Area

63.353

Acid Dissociation Constant (pKa)

5.56

Base Dissociation Constant (pKb)

-2.94

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

15.80

D294-0768 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

C-Met Library (15277 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Agro:
  • Agro
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D294-0768 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D294-0768?
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What is the minimum amount of D294-0768 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D294-0768
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D294-0768
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D294-0768 available by request