D294-1010 Screening compound: N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3,4-dimethoxybenzamide

D294-1010 Screening compound: N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3,4-dimethoxybenzamide
D294-1010 Screening compound: N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3,4-dimethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D294-1010
N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3,4-dimethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D294-1010

Molecular Formula

C21H19ClN4O4S (C21 H19 ClN4 O4 S)

Compound Name

N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3,4-dimethoxybenzamide

IUPAC name

N-{5-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]-134-thiadiazol-2-yl}-34-dimethoxybenzamide

SMILES

COc(ccc(C(Nc1nnc(C(CC2=O)CN2c(cc2)ccc2Cl)s1)=O)c1)c1OC

InChI

InChI=1S/C21H19ClN4O4S/c1-29-16-8-3-12(9-17(16)30-2)19(28)23-21-25-24-20(31-21)13-10-18(27)26(11-13)15-6-4-14(22)5-7-15/h3-9,13H,10-11H2,1-2H3,(H,23,25,28)/t13-/m1/s1

InChI Key

HASJNNNMEVWBTO-CYBMUJFWSA-N

MDL Number (MFCD)

MFCD09270564

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.93

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.390

Distribution Coefficient, logD

3.095

Water Solubility, LogSw

-3.98

Polar Surface Area

78.614

Acid Dissociation Constant (pKa)

7.41

Base Dissociation Constant (pKb)

-2.94

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.80

D294-1010 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D294-1010 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D294-1010?
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What is the minimum amount of D294-1010 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D294-1010
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D294-1010
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D294-1010 available by request