D294-1091 Screening compound: N-{5-[1-(3,5-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}furan-2-carboxamide

D294-1091 Screening compound: N-{5-[1-(3,5-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}furan-2-carboxamide
D294-1091 Screening compound: N-{5-[1-(3,5-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D294-1091
N-{5-[1-(3,5-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D294-1091

Molecular Formula

C19H18N4O3S (C19 H18 N4 O3 S)

Compound Name

N-{5-[1-(3,5-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}furan-2-carboxamide

IUPAC name

N-{5-[1-(35-dimethylphenyl)-5-oxopyrrolidin-3-yl]-134-thiadiazol-2-yl}furan-2-carboxamide

SMILES

Cc1cc(N(CC(C2)c3nnc(NC(c4ccco4)=O)s3)C2=O)cc(C)c1

InChI

InChI=1S/C19H18N4O3S/c1-11-6-12(2)8-14(7-11)23-10-13(9-16(23)24)18-21-22-19(27-18)20-17(25)15-4-3-5-26-15/h3-8,13H,9-10H2,1-2H3,(H,20,22,25)/t13-/m0/s1

InChI Key

JSGNREZJSREPTI-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD09270570

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.429

Distribution Coefficient, logD

2.847

Water Solubility, LogSw

-3.64

Polar Surface Area

71.931

Acid Dissociation Constant (pKa)

6.95

Base Dissociation Constant (pKb)

-2.11

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.30

D294-1091 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D294-1091 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D294-1091?
Check Price and Availability of D294-1091, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D294-1091 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D294-1091
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D294-1091
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D294-1091 available by request