D294-1214 Screening compound: 4-acetamido-N-{5-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}benzamide

D294-1214 Screening compound: 4-acetamido-N-{5-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}benzamide
D294-1214 Screening compound: 4-acetamido-N-{5-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D294-1214
4-acetamido-N-{5-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D294-1214

Molecular Formula

C22H21N5O4S (C22 H21 N5 O4 S)

Compound Name

4-acetamido-N-{5-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}benzamide

IUPAC name

4-acetamido-N-{5-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]-134-thiadiazol-2-yl}benzamide

SMILES

CC(Nc(cc1)ccc1C(Nc1nnc(C(CC2=O)CN2c(cc2)ccc2OC)s1)=O)=O

InChI

InChI=1S/C22H21N5O4S/c1-13(28)23-16-5-3-14(4-6-16)20(30)24-22-26-25-21(32-22)15-11-19(29)27(12-15)17-7-9-18(31-2)10-8-17/h3-10,15H,11-12H2,1-2H3,(H,23,28)(H,24,26,30)/t15-/m0/s1

InChI Key

RKNPHARCGWJNJN-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD09271435

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.51

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.354

Distribution Coefficient, logD

1.222

Water Solubility, LogSw

-2.80

Polar Surface Area

94.159

Acid Dissociation Constant (pKa)

6.30

Base Dissociation Constant (pKb)

-0.73

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.70

D294-1214 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D294-1214 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D294-1214?
Check Price and Availability of D294-1214, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D294-1214 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D294-1214
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D294-1214
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D294-1214 available by request