D294-1267 Screening compound: N-{5-[1-(3,5-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}acetamide

D294-1267 Screening compound: N-{5-[1-(3,5-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}acetamide
D294-1267 Screening compound: N-{5-[1-(3,5-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D294-1267
N-{5-[1-(3,5-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D294-1267

Molecular Formula

C16H18N4O2S (C16 H18 N4 O2 S)

Compound Name

N-{5-[1-(3,5-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}acetamide

IUPAC name

N-{5-[1-(35-dimethylphenyl)-5-oxopyrrolidin-3-yl]-134-thiadiazol-2-yl}acetamide

SMILES

CC(Nc1nnc(C(CC2=O)CN2c2cc(C)cc(C)c2)s1)=O

InChI

InChI=1S/C16H18N4O2S/c1-9-4-10(2)6-13(5-9)20-8-12(7-14(20)22)15-18-19-16(23-15)17-11(3)21/h4-6,12H,7-8H2,1-3H3,(H,17,19,21)/t12-/m0/s1

InChI Key

NQRUAKGDHMOJHQ-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD09270410

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

330.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.643

Distribution Coefficient, logD

2.587

Water Solubility, LogSw

-2.86

Polar Surface Area

63.524

Acid Dissociation Constant (pKa)

8.26

Base Dissociation Constant (pKb)

-2.11

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

D294-1267 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

CNS MPO Library (28609 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Nervous system
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D294-1267 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D294-1267?
Check Price and Availability of D294-1267, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D294-1267 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D294-1267
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D294-1267
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D294-1267 available by request