D294-1822 Screening compound: N-{5-[1-(2-ethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3-phenylpropanamide

D294-1822 Screening compound: N-{5-[1-(2-ethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3-phenylpropanamide
D294-1822 Screening compound: N-{5-[1-(2-ethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3-phenylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D294-1822
N-{5-[1-(2-ethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3-phenylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D294-1822

Molecular Formula

C23H24N4O2S (C23 H24 N4 O2 S)

Compound Name

N-{5-[1-(2-ethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3-phenylpropanamide

IUPAC name

N-{5-[1-(2-ethylphenyl)-5-oxopyrrolidin-3-yl]-134-thiadiazol-2-yl}-3-phenylpropanamide

SMILES

CCc(cccc1)c1N(CC(C1)c2nnc(NC(CCc3ccccc3)=O)s2)C1=O

InChI

InChI=1S/C23H24N4O2S/c1-2-17-10-6-7-11-19(17)27-15-18(14-21(27)29)22-25-26-23(30-22)24-20(28)13-12-16-8-4-3-5-9-16/h3-11,18H,2,12-15H2,1H3,(H,24,26,28)/t18-/m0/s1

InChI Key

TVLIKVKCJCAPMM-SFHVURJKSA-N

MDL Number (MFCD)

MFCD09270425

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.348

Distribution Coefficient, logD

4.049

Water Solubility, LogSw

-4.20

Polar Surface Area

62.839

Acid Dissociation Constant (pKa)

7.40

Base Dissociation Constant (pKb)

-1.53

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.40

D294-1822 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D294-1822 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D294-1822?
Check Price and Availability of D294-1822, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D294-1822 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D294-1822
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D294-1822
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D294-1822 available by request