D294-3325 Screening compound: N-{5-[1-(2-methylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3-(phenylsulfanyl)propanamide

D294-3325 Screening compound: N-{5-[1-(2-methylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3-(phenylsulfanyl)propanamide
D294-3325 Screening compound: N-{5-[1-(2-methylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3-(phenylsulfanyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D294-3325
N-{5-[1-(2-methylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3-(phenylsulfanyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D294-3325

Molecular Formula

C22H22N4O2S2 (C22 H22 N4 O2 S2)

Compound Name

N-{5-[1-(2-methylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-3-(phenylsulfanyl)propanamide

IUPAC name

N-{5-[1-(2-methylphenyl)-5-oxopyrrolidin-3-yl]-134-thiadiazol-2-yl}-3-(phenylsulfanyl)propanamide

SMILES

Cc(cccc1)c1N(CC(C1)c2nnc(NC(CCSc3ccccc3)=O)s2)C1=O

InChI

InChI=1S/C22H22N4O2S2/c1-15-7-5-6-10-18(15)26-14-16(13-20(26)28)21-24-25-22(30-21)23-19(27)11-12-29-17-8-3-2-4-9-17/h2-10,16H,11-14H2,1H3,(H,23,25,27)/t16-/m0/s1

InChI Key

MMAMDQLPVDVEKH-INIZCTEOSA-N

MDL Number (MFCD)

MFCD09270631

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.010

Distribution Coefficient, logD

3.743

Water Solubility, LogSw

-4.06

Polar Surface Area

62.839

Acid Dissociation Constant (pKa)

7.47

Base Dissociation Constant (pKb)

-2.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.27

D294-3325 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D294-3325 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D294-3325?
Check Price and Availability of D294-3325, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D294-3325 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D294-3325
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D294-3325
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D294-3325 available by request