D294-3497 Screening compound: 2-(benzenesulfonyl)-N-{5-[1-(3-chloro-4-methylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}acetamide

D294-3497 Screening compound: 2-(benzenesulfonyl)-N-{5-[1-(3-chloro-4-methylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}acetamide
D294-3497 Screening compound: 2-(benzenesulfonyl)-N-{5-[1-(3-chloro-4-methylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D294-3497
2-(benzenesulfonyl)-N-{5-[1-(3-chloro-4-methylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D294-3497

Molecular Formula

C21H19ClN4O4S2 (C21 H19 ClN4 O4 S2)

Compound Name

2-(benzenesulfonyl)-N-{5-[1-(3-chloro-4-methylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}acetamide

IUPAC name

2-(benzenesulfonyl)-N-{5-[1-(3-chloro-4-methylphenyl)-5-oxopyrrolidin-3-yl]-134-thiadiazol-2-yl}acetamide

SMILES

Cc(ccc(N(CC(C1)c2nnc(NC(CS(c3ccccc3)(=O)=O)=O)s2)C1=O)c1)c1Cl

InChI

InChI=1S/C21H19ClN4O4S2/c1-13-7-8-15(10-17(13)22)26-11-14(9-19(26)28)20-24-25-21(31-20)23-18(27)12-32(29,30)16-5-3-2-4-6-16/h2-8,10,14H,9,11-12H2,1H3,(H,23,25,27)/t14-/m1/s1

InChI Key

QZEYATOOXXRXFY-CQSZACIVSA-N

MDL Number (MFCD)

MFCD09270489

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.99

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.298

Distribution Coefficient, logD

3.106

Water Solubility, LogSw

-3.51

Polar Surface Area

92.176

Acid Dissociation Constant (pKa)

7.66

Base Dissociation Constant (pKb)

-2.51

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.80

D294-3497 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D294-3497 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D294-3497?
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What is the minimum amount of D294-3497 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D294-3497
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D294-3497
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D294-3497 available by request