D294-3532 Screening compound: N-{5-[1-(3,4-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-4-propanamidobenzamide

D294-3532 Screening compound: N-{5-[1-(3,4-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-4-propanamidobenzamide
D294-3532 Screening compound: N-{5-[1-(3,4-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-4-propanamidobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D294-3532
N-{5-[1-(3,4-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-4-propanamidobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D294-3532

Molecular Formula

C24H25N5O3S (C24 H25 N5 O3 S)

Compound Name

N-{5-[1-(3,4-dimethylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-thiadiazol-2-yl}-4-propanamidobenzamide

IUPAC name

N-{5-[1-(34-dimethylphenyl)-5-oxopyrrolidin-3-yl]-134-thiadiazol-2-yl}-4-propanamidobenzamide

SMILES

CCC(Nc(cc1)ccc1C(Nc1nnc(C(CC2=O)CN2c2cc(C)c(C)cc2)s1)=O)=O

InChI

InChI=1S/C24H25N5O3S/c1-4-20(30)25-18-8-6-16(7-9-18)22(32)26-24-28-27-23(33-24)17-12-21(31)29(13-17)19-10-5-14(2)15(3)11-19/h5-11,17H,4,12-13H2,1-3H3,(H,25,30)(H,26,28,32)/t17-/m0/s1

InChI Key

PKXWXJVCETVQCR-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD09271583

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.56

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.987

Distribution Coefficient, logD

2.855

Water Solubility, LogSw

-3.98

Polar Surface Area

86.502

Acid Dissociation Constant (pKa)

6.30

Base Dissociation Constant (pKb)

-0.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.20

D294-3532 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Infections
  • Immune system
  • animal
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D294-3532 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D294-3532?
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What is the minimum amount of D294-3532 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D294-3532
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D294-3532
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D294-3532 available by request