D294-4879 Screening compound: 1-[2-(5-chloro-1H-indol-3-yl)ethyl]-4-(morpholine-4-carbonyl)pyrrolidin-2-one

D294-4879 Screening compound: 1-[2-(5-chloro-1H-indol-3-yl)ethyl]-4-(morpholine-4-carbonyl)pyrrolidin-2-one
D294-4879 Screening compound: 1-[2-(5-chloro-1H-indol-3-yl)ethyl]-4-(morpholine-4-carbonyl)pyrrolidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D294-4879
1-[2-(5-chloro-1H-indol-3-yl)ethyl]-4-(morpholine-4-carbonyl)pyrrolidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D294-4879

Molecular Formula

C19H22ClN3O3 (C19 H22 ClN3 O3)

Compound Name

1-[2-(5-chloro-1H-indol-3-yl)ethyl]-4-(morpholine-4-carbonyl)pyrrolidin-2-one

IUPAC name

1-[2-(5-chloro-1H-indol-3-yl)ethyl]-4-(morpholine-4-carbonyl)pyrrolidin-2-one

SMILES

O=C(C(C1)CN(CCc2c[nH]c(cc3)c2cc3Cl)C1=O)N1CCOCC1

InChI

InChI=1S/C19H22ClN3O3/c20-15-1-2-17-16(10-15)13(11-21-17)3-4-23-12-14(9-18(23)24)19(25)22-5-7-26-8-6-22/h1-2,10-11,14,21H,3-9,12H2/t14-/m1/s1

InChI Key

QKTVULLEAMGYJO-CQSZACIVSA-N

MDL Number (MFCD)

MFCD09270656

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.85

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.262

Distribution Coefficient, logD

1.262

Water Solubility, LogSw

-2.59

Polar Surface Area

51.840

Acid Dissociation Constant (pKa)

15.37

Base Dissociation Constant (pKb)

-2.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

47.40

D294-4879 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Soluble Diversity Library (15920 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with D294-4879 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D294-4879?
Check Price and Availability of D294-4879, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D294-4879 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D294-4879
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D294-4879
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D294-4879 available by request