D295-0186 Screening compound: 6-methyl-3-({[4-(piperidin-1-yl)-2-(pyrrolidine-1-carbonyl)phenyl]amino}methyl)-1,2-dihydroquinolin-2-one

D295-0186 Screening compound: 6-methyl-3-({[4-(piperidin-1-yl)-2-(pyrrolidine-1-carbonyl)phenyl]amino}methyl)-1,2-dihydroquinolin-2-one
D295-0186 Screening compound: 6-methyl-3-({[4-(piperidin-1-yl)-2-(pyrrolidine-1-carbonyl)phenyl]amino}methyl)-1,2-dihydroquinolin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D295-0186
6-methyl-3-({[4-(piperidin-1-yl)-2-(pyrrolidine-1-carbonyl)phenyl]amino}methyl)-1,2-dihydroquinolin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D295-0186

Molecular Formula

C27H32N4O2 (C27 H32 N4 O2)

Compound Name

6-methyl-3-({[4-(piperidin-1-yl)-2-(pyrrolidine-1-carbonyl)phenyl]amino}methyl)-1,2-dihydroquinolin-2-one

IUPAC name

6-methyl-3-({[4-(piperidin-1-yl)-2-(pyrrolidine-1-carbonyl)phenyl]amino}methyl)-12-dihydroquinolin-2-one

SMILES

Cc(cc1)cc(C=C2CNc(ccc(N3CCCCC3)c3)c3C(N3CCCC3)=O)c1NC2=O

InChI

InChI=1S/C27H32N4O2/c1-19-7-9-24-20(15-19)16-21(26(32)29-24)18-28-25-10-8-22(30-11-3-2-4-12-30)17-23(25)27(33)31-13-5-6-14-31/h7-10,15-17,28H,2-6,11-14,18H2,1H3,(H,29,32)

InChI Key

OJVPCXNRHQDCIU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14816970

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.58

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.370

Distribution Coefficient, logD

4.369

Water Solubility, LogSw

-4.19

Polar Surface Area

55.120

Acid Dissociation Constant (pKa)

12.06

Base Dissociation Constant (pKb)

10.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.70

D295-0186 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Immunological Library (6760 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with D295-0186 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D295-0186?
Check Price and Availability of D295-0186, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D295-0186 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D295-0186
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D295-0186
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D295-0186 available by request