D299-0116 Screening compound: 5-chloro-N-[3-(3,4-difluorophenyl)-1,2-oxazol-5-yl]-3-methyl-1-benzofuran-2-carboxamide

D299-0116 Screening compound: 5-chloro-N-[3-(3,4-difluorophenyl)-1,2-oxazol-5-yl]-3-methyl-1-benzofuran-2-carboxamide
D299-0116 Screening compound: 5-chloro-N-[3-(3,4-difluorophenyl)-1,2-oxazol-5-yl]-3-methyl-1-benzofuran-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D299-0116
5-chloro-N-[3-(3,4-difluorophenyl)-1,2-oxazol-5-yl]-3-methyl-1-benzofuran-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D299-0116

Molecular Formula

C19H11ClF2N2O3 (C19 H11 ClF2 N2 O3)

Compound Name

5-chloro-N-[3-(3,4-difluorophenyl)-1,2-oxazol-5-yl]-3-methyl-1-benzofuran-2-carboxamide

IUPAC name

5-chloro-N-[3-(34-difluorophenyl)-12-oxazol-5-yl]-3-methyl-1-benzofuran-2-carboxamide

SMILES

Cc1c(C(Nc2cc(-c(cc3)cc(F)c3F)no2)=O)oc(cc2)c1cc2Cl

InChI

InChI=1S/C19H11ClF2N2O3/c1-9-12-7-11(20)3-5-16(12)26-18(9)19(25)23-17-8-15(24-27-17)10-2-4-13(21)14(22)6-10/h2-8H,1H3,(H,23,25)

InChI Key

WVLQHOVKLFZLAU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08549297

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.76

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.797

Distribution Coefficient, logD

5.787

Water Solubility, LogSw

-6.12

Polar Surface Area

54.136

Acid Dissociation Constant (pKa)

9.03

Base Dissociation Constant (pKb)

-5.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

D299-0116 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Immune system
  • Cancer
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D299-0116 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D299-0116?
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What is the minimum amount of D299-0116 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D299-0116
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D299-0116
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D299-0116 available by request