D305-0284 Screening compound: N-{2-[(4-ethylpiperazin-1-yl)methyl]-1-propyl-1H-1,3-benzodiazol-5-yl}-2-phenoxyacetamide

D305-0284 Screening compound: N-{2-[(4-ethylpiperazin-1-yl)methyl]-1-propyl-1H-1,3-benzodiazol-5-yl}-2-phenoxyacetamide
D305-0284 Screening compound: N-{2-[(4-ethylpiperazin-1-yl)methyl]-1-propyl-1H-1,3-benzodiazol-5-yl}-2-phenoxyacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D305-0284
N-{2-[(4-ethylpiperazin-1-yl)methyl]-1-propyl-1H-1,3-benzodiazol-5-yl}-2-phenoxyacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D305-0284

Molecular Formula

C25H33N5O2 (C25 H33 N5 O2)

Compound Name

N-{2-[(4-ethylpiperazin-1-yl)methyl]-1-propyl-1H-1,3-benzodiazol-5-yl}-2-phenoxyacetamide

IUPAC name

N-{2-[(4-ethylpiperazin-1-yl)methyl]-1-propyl-1H-13-benzodiazol-5-yl}-2-phenoxyacetamide

SMILES

CCCn1c(ccc(NC(COc2ccccc2)=O)c2)c2nc1CN1CCN(CC)CC1

InChI

InChI=1S/C25H33N5O2/c1-3-12-30-23-11-10-20(26-25(31)19-32-21-8-6-5-7-9-21)17-22(23)27-24(30)18-29-15-13-28(4-2)14-16-29/h5-11,17H,3-4,12-16,18-19H2,1-2H3,(H,26,31)

InChI Key

XNSFAMAYHACEHX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09767165

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.558

Distribution Coefficient, logD

2.447

Water Solubility, LogSw

-3.64

Polar Surface Area

49.039

Acid Dissociation Constant (pKa)

12.44

Base Dissociation Constant (pKb)

8.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

D305-0284 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MCL1 Targeted Library (12200 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Nucleic Acid Ligands (8311 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with D305-0284 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D305-0284?
Check Price and Availability of D305-0284, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D305-0284 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D305-0284
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D305-0284
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D305-0284 available by request