D305-0370 Screening compound: N-{2-[(4-benzylpiperazin-1-yl)methyl]-1-methyl-1H-1,3-benzodiazol-5-yl}pentanamide

D305-0370 Screening compound: N-{2-[(4-benzylpiperazin-1-yl)methyl]-1-methyl-1H-1,3-benzodiazol-5-yl}pentanamide
D305-0370 Screening compound: N-{2-[(4-benzylpiperazin-1-yl)methyl]-1-methyl-1H-1,3-benzodiazol-5-yl}pentanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D305-0370
N-{2-[(4-benzylpiperazin-1-yl)methyl]-1-methyl-1H-1,3-benzodiazol-5-yl}pentanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D305-0370

Molecular Formula

C25H33N5O (C25 H33 N5 O)

Compound Name

N-{2-[(4-benzylpiperazin-1-yl)methyl]-1-methyl-1H-1,3-benzodiazol-5-yl}pentanamide

IUPAC name

N-{2-[(4-benzylpiperazin-1-yl)methyl]-1-methyl-1H-13-benzodiazol-5-yl}pentanamide

SMILES

CCCCC(Nc(cc1)cc2c1n(C)c(CN1CCN(Cc3ccccc3)CC1)n2)=O

InChI

InChI=1S/C25H33N5O/c1-3-4-10-25(31)26-21-11-12-23-22(17-21)27-24(28(23)2)19-30-15-13-29(14-16-30)18-20-8-6-5-7-9-20/h5-9,11-12,17H,3-4,10,13-16,18-19H2,1-2H3,(H,26,31)

InChI Key

SYXGRBKEFJTDDX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09222873

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.297

Distribution Coefficient, logD

2.991

Water Solubility, LogSw

-3.55

Polar Surface Area

42.647

Acid Dissociation Constant (pKa)

12.30

Base Dissociation Constant (pKb)

7.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

D305-0370 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D305-0370 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D305-0370?
Check Price and Availability of D305-0370, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D305-0370 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D305-0370
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D305-0370
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D305-0370 available by request