D306-0208 Screening compound: ethyl 4-methyl-2-{2-[(6-phenylpyrimidin-4-yl)sulfanyl]acetamido}-1,3-thiazole-5-carboxylate

D306-0208 Screening compound: ethyl 4-methyl-2-{2-[(6-phenylpyrimidin-4-yl)sulfanyl]acetamido}-1,3-thiazole-5-carboxylate
D306-0208 Screening compound: ethyl 4-methyl-2-{2-[(6-phenylpyrimidin-4-yl)sulfanyl]acetamido}-1,3-thiazole-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound D306-0208
ethyl 4-methyl-2-{2-[(6-phenylpyrimidin-4-yl)sulfanyl]acetamido}-1,3-thiazole-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D306-0208

Molecular Formula

C19H18N4O3S2 (C19 H18 N4 O3 S2)

Compound Name

ethyl 4-methyl-2-{2-[(6-phenylpyrimidin-4-yl)sulfanyl]acetamido}-1,3-thiazole-5-carboxylate

IUPAC name

ethyl 4-methyl-2-{2-[(6-phenylpyrimidin-4-yl)sulfanyl]acetamido}-13-thiazole-5-carboxylate

SMILES

CCOC(c1c(C)nc(NC(CSc2ncnc(-c3ccccc3)c2)=O)s1)=O

InChI

InChI=1S/C19H18N4O3S2/c1-3-26-18(25)17-12(2)22-19(28-17)23-15(24)10-27-16-9-14(20-11-21-16)13-7-5-4-6-8-13/h4-9,11H,3,10H2,1-2H3,(H,22,23,24)

InChI Key

HTVINOVYSPKWIF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10480155

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.51

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.141

Distribution Coefficient, logD

4.093

Water Solubility, LogSw

-4.11

Polar Surface Area

73.393

Acid Dissociation Constant (pKa)

8.34

Base Dissociation Constant (pKb)

3.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

D306-0208 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D306-0208 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D306-0208?
Check Price and Availability of D306-0208, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D306-0208 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D306-0208
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D306-0208
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D306-0208 available by request