D306-0262 Screening compound: 1-(1H-indol-3-yl)-2-[(6-phenylpyrimidin-4-yl)sulfanyl]ethan-1-one

D306-0262 Screening compound: 1-(1H-indol-3-yl)-2-[(6-phenylpyrimidin-4-yl)sulfanyl]ethan-1-one
D306-0262 Screening compound: 1-(1H-indol-3-yl)-2-[(6-phenylpyrimidin-4-yl)sulfanyl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D306-0262
1-(1H-indol-3-yl)-2-[(6-phenylpyrimidin-4-yl)sulfanyl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D306-0262

Molecular Formula

C20H15N3OS (C20 H15 N3 OS)

Compound Name

1-(1H-indol-3-yl)-2-[(6-phenylpyrimidin-4-yl)sulfanyl]ethan-1-one

IUPAC name

1-(1H-indol-3-yl)-2-[(6-phenylpyrimidin-4-yl)sulfanyl]ethan-1-one

SMILES

O=C(CSc1ncnc(-c2ccccc2)c1)c1c[nH]c2c1cccc2

InChI

InChI=1S/C20H15N3OS/c24-19(16-11-21-17-9-5-4-8-15(16)17)12-25-20-10-18(22-13-23-20)14-6-2-1-3-7-14/h1-11,13,21H,12H2

InChI Key

LQFFRBQRESUZKO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09982366

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

345.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.646

Distribution Coefficient, logD

4.646

Water Solubility, LogSw

-4.57

Polar Surface Area

41.984

Acid Dissociation Constant (pKa)

16.73

Base Dissociation Constant (pKb)

3.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.00

D306-0262 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Immunological Library (6760 compounds)

Akt-Targeted Library (14764 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases
  • Others

References: we are preparing a list of scientific research reports with D306-0262 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D306-0262?
Check Price and Availability of D306-0262, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D306-0262 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D306-0262
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D306-0262
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D306-0262 available by request