D306-0303 Screening compound: 4-{[(2-fluorophenyl)methyl]sulfanyl}-2-methyl-6-phenylpyrimidine

D306-0303 Screening compound: 4-{[(2-fluorophenyl)methyl]sulfanyl}-2-methyl-6-phenylpyrimidine
D306-0303 Screening compound: 4-{[(2-fluorophenyl)methyl]sulfanyl}-2-methyl-6-phenylpyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound D306-0303
4-{[(2-fluorophenyl)methyl]sulfanyl}-2-methyl-6-phenylpyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D306-0303

Molecular Formula

C18H15FN2S (C18 H15 FN2 S)

Compound Name

4-{[(2-fluorophenyl)methyl]sulfanyl}-2-methyl-6-phenylpyrimidine

IUPAC name

4-{[(2-fluorophenyl)methyl]sulfanyl}-2-methyl-6-phenylpyrimidine

SMILES

Cc1nc(-c2ccccc2)cc(SCc(cccc2)c2F)n1

InChI

InChI=1S/C18H15FN2S/c1-13-20-17(14-7-3-2-4-8-14)11-18(21-13)22-12-15-9-5-6-10-16(15)19/h2-11H,12H2,1H3

InChI Key

ALWBSQGHRQTFJA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10480172

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

310.39

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

5.262

Distribution Coefficient, logD

5.260

Water Solubility, LogSw

-5.31

Polar Surface Area

17.240

Acid Dissociation Constant (pKa)

24.25

Base Dissociation Constant (pKb)

5.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

D306-0303 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

GABA Library (7115 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D306-0303 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D306-0303?
Check Price and Availability of D306-0303, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D306-0303 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D306-0303
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D306-0303
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D306-0303 available by request