D308-0486 Screening compound: 2,4-dimethyl-N-{4-[4-(propan-2-yloxy)phenyl]-1,3-thiazol-2-yl}-1,3-thiazole-5-carboxamide

D308-0486 Screening compound: 2,4-dimethyl-N-{4-[4-(propan-2-yloxy)phenyl]-1,3-thiazol-2-yl}-1,3-thiazole-5-carboxamide
D308-0486 Screening compound: 2,4-dimethyl-N-{4-[4-(propan-2-yloxy)phenyl]-1,3-thiazol-2-yl}-1,3-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D308-0486
2,4-dimethyl-N-{4-[4-(propan-2-yloxy)phenyl]-1,3-thiazol-2-yl}-1,3-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D308-0486

Molecular Formula

C18H19N3O2S2 (C18 H19 N3 O2 S2)

Compound Name

2,4-dimethyl-N-{4-[4-(propan-2-yloxy)phenyl]-1,3-thiazol-2-yl}-1,3-thiazole-5-carboxamide

IUPAC name

24-dimethyl-N-{4-[4-(propan-2-yloxy)phenyl]-13-thiazol-2-yl}-13-thiazole-5-carboxamide

SMILES

CC(C)Oc(cc1)ccc1-c1csc(NC(c2c(C)nc(C)s2)=O)n1

InChI

InChI=1S/C18H19N3O2S2/c1-10(2)23-14-7-5-13(6-8-14)15-9-24-18(20-15)21-17(22)16-11(3)19-12(4)25-16/h5-10H,1-4H3,(H,20,21,22)

InChI Key

RWEZUWZQBAPLKH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08568437

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.026

Distribution Coefficient, logD

5.025

Water Solubility, LogSw

-4.56

Polar Surface Area

50.296

Acid Dissociation Constant (pKa)

10.12

Base Dissociation Constant (pKb)

1.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

D308-0486 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Angiogenesis library (14822 compounds)

Anti-Inflammatory Library (24602 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D308-0486 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D308-0486?
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What is the minimum amount of D308-0486 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D308-0486
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D308-0486
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D308-0486 available by request