D315-1200 Screening compound: N-(4-fluorophenyl)-2-{3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]-6-oxo-1,6-dihydropyridazin-1-yl}propanamide

D315-1200 Screening compound: N-(4-fluorophenyl)-2-{3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]-6-oxo-1,6-dihydropyridazin-1-yl}propanamide
D315-1200 Screening compound: N-(4-fluorophenyl)-2-{3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]-6-oxo-1,6-dihydropyridazin-1-yl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D315-1200
N-(4-fluorophenyl)-2-{3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]-6-oxo-1,6-dihydropyridazin-1-yl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D315-1200

Molecular Formula

C25H27FN4O4S (C25 H27 FN4 O4 S)

Compound Name

N-(4-fluorophenyl)-2-{3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]-6-oxo-1,6-dihydropyridazin-1-yl}propanamide

IUPAC name

N-(4-fluorophenyl)-2-{3-[4-methyl-3-(piperidine-1-sulfonyl)phenyl]-6-oxo-16-dihydropyridazin-1-yl}propanamide

SMILES

CC(C(Nc(cc1)ccc1F)=O)N(C(C=C1)=O)N=C1c1cc(S(N2CCCCC2)(=O)=O)c(C)cc1

InChI

InChI=1S/C25H27FN4O4S/c1-17-6-7-19(16-23(17)35(33,34)29-14-4-3-5-15-29)22-12-13-24(31)30(28-22)18(2)25(32)27-21-10-8-20(26)9-11-21/h6-13,16,18H,3-5,14-15H2,1-2H3,(H,27,32)/t18-/m0/s1

InChI Key

VHTRDGLFOBWFKI-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27580070

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.58

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.891

Distribution Coefficient, logD

3.891

Water Solubility, LogSw

-3.95

Polar Surface Area

82.154

Acid Dissociation Constant (pKa)

11.13

Base Dissociation Constant (pKb)

-0.34

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

32.00

D315-1200 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D315-1200 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D315-1200?
Check Price and Availability of D315-1200, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D315-1200 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D315-1200
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D315-1200
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D315-1200 available by request