D319-0357 Screening compound: N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}-4-methyl-1,2,3-thiadiazole-5-carboxamide

D319-0357 Screening compound: N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}-4-methyl-1,2,3-thiadiazole-5-carboxamide
D319-0357 Screening compound: N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}-4-methyl-1,2,3-thiadiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D319-0357
N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}-4-methyl-1,2,3-thiadiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D319-0357

Molecular Formula

C15H15N5O4S2 (C15 H15 N5 O4 S2)

Compound Name

N-{4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl}-4-methyl-1,2,3-thiadiazole-5-carboxamide

IUPAC name

N-{4-[(34-dimethyl-12-oxazol-5-yl)sulfamoyl]phenyl}-4-methyl-123-thiadiazole-5-carboxamide

SMILES

Cc1c(NS(c(cc2)ccc2NC(c2c(C)nns2)=O)(=O)=O)onc1C

InChI

InChI=1S/C15H15N5O4S2/c1-8-9(2)18-24-15(8)19-26(22,23)12-6-4-11(5-7-12)16-14(21)13-10(3)17-20-25-13/h4-7,19H,1-3H3,(H,16,21)

InChI Key

XLXUFPOWPYGKLV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08545851

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.45

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.668

Distribution Coefficient, logD

-0.341

Water Solubility, LogSw

-2.83

Polar Surface Area

109.087

Acid Dissociation Constant (pKa)

5.40

Base Dissociation Constant (pKb)

-1.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

D319-0357 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D319-0357 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D319-0357?
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What is the minimum amount of D319-0357 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D319-0357
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D319-0357
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D319-0357 available by request