D337-0836 Screening compound: N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-chlorophenyl)-1,2-oxazole-3-carboxamide

D337-0836 Screening compound: N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-chlorophenyl)-1,2-oxazole-3-carboxamide
D337-0836 Screening compound: N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-chlorophenyl)-1,2-oxazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D337-0836
N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-chlorophenyl)-1,2-oxazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D337-0836

Molecular Formula

C16H12ClN3O3S (C16 H12 ClN3 O3 S)

Compound Name

N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-5-(4-chlorophenyl)-1,2-oxazole-3-carboxamide

IUPAC name

N-(5-acetyl-4-methyl-13-thiazol-2-yl)-5-(4-chlorophenyl)-12-oxazole-3-carboxamide

SMILES

CC(c1c(C)nc(NC(c2noc(-c(cc3)ccc3Cl)c2)=O)s1)=O

InChI

InChI=1S/C16H12ClN3O3S/c1-8-14(9(2)21)24-16(18-8)19-15(22)12-7-13(23-20-12)10-3-5-11(17)6-4-10/h3-7H,1-2H3,(H,18,19,22)

InChI Key

MMCZIZGAHBLRRZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08545169

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.81

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.048

Distribution Coefficient, logD

3.751

Water Solubility, LogSw

-4.48

Polar Surface Area

69.315

Acid Dissociation Constant (pKa)

7.41

Base Dissociation Constant (pKb)

-2.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

D337-0836 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with D337-0836 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D337-0836?
Check Price and Availability of D337-0836, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D337-0836 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D337-0836
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D337-0836
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D337-0836 available by request