D337-0837 Screening compound: methyl 2-[5-(4-chlorophenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate

D337-0837 Screening compound: methyl 2-[5-(4-chlorophenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate
D337-0837 Screening compound: methyl 2-[5-(4-chlorophenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound D337-0837
methyl 2-[5-(4-chlorophenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D337-0837

Molecular Formula

C16H12ClN3O4S (C16 H12 ClN3 O4 S)

Compound Name

methyl 2-[5-(4-chlorophenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate

IUPAC name

methyl 2-[5-(4-chlorophenyl)-12-oxazole-3-amido]-4-methyl-13-thiazole-5-carboxylate

SMILES

Cc1c(C(OC)=O)sc(NC(c2noc(-c(cc3)ccc3Cl)c2)=O)n1

InChI

InChI=1S/C16H12ClN3O4S/c1-8-13(15(22)23-2)25-16(18-8)19-14(21)11-7-12(24-20-11)9-3-5-10(17)6-4-9/h3-7H,1-2H3,(H,18,19,21)

InChI Key

XKEKQZLAFFAOME-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08544916

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.81

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.226

Distribution Coefficient, logD

4.153

Water Solubility, LogSw

-4.65

Polar Surface Area

76.662

Acid Dissociation Constant (pKa)

8.14

Base Dissociation Constant (pKb)

-0.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

D337-0837 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Antiviral Library (67538 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D337-0837 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D337-0837?
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What is the minimum amount of D337-0837 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D337-0837
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D337-0837
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D337-0837 available by request