D337-0886 Screening compound: 2-methylpropyl 2-[5-(4-chlorophenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate

D337-0886 Screening compound: 2-methylpropyl 2-[5-(4-chlorophenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate
D337-0886 Screening compound: 2-methylpropyl 2-[5-(4-chlorophenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound D337-0886
2-methylpropyl 2-[5-(4-chlorophenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D337-0886

Molecular Formula

C19H18ClN3O4S (C19 H18 ClN3 O4 S)

Compound Name

2-methylpropyl 2-[5-(4-chlorophenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate

IUPAC name

2-methylpropyl 2-[5-(4-chlorophenyl)-12-oxazole-3-amido]-4-methyl-13-thiazole-5-carboxylate

SMILES

CC(C)COC(c1c(C)nc(NC(c2noc(-c(cc3)ccc3Cl)c2)=O)s1)=O

InChI

InChI=1S/C19H18ClN3O4S/c1-10(2)9-26-18(25)16-11(3)21-19(28-16)22-17(24)14-8-15(27-23-14)12-4-6-13(20)7-5-12/h4-8,10H,9H2,1-3H3,(H,21,22,24)

InChI Key

PCYFJISBDPITAR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08545173

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.89

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.399

Distribution Coefficient, logD

5.326

Water Solubility, LogSw

-6.03

Polar Surface Area

76.617

Acid Dissociation Constant (pKa)

8.14

Base Dissociation Constant (pKb)

-0.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

D337-0886 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Antiviral Library (67538 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D337-0886 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D337-0886?
Check Price and Availability of D337-0886, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D337-0886 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D337-0886
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D337-0886
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D337-0886 available by request