D337-1132 Screening compound: 5-(2-methyl-2,3-dihydro-1-benzofuran-5-yl)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1,2-oxazole-3-carboxamide

D337-1132 Screening compound: 5-(2-methyl-2,3-dihydro-1-benzofuran-5-yl)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1,2-oxazole-3-carboxamide
D337-1132 Screening compound: 5-(2-methyl-2,3-dihydro-1-benzofuran-5-yl)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1,2-oxazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D337-1132
5-(2-methyl-2,3-dihydro-1-benzofuran-5-yl)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1,2-oxazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D337-1132

Molecular Formula

C24H21N5O5S (C24 H21 N5 O5 S)

Compound Name

5-(2-methyl-2,3-dihydro-1-benzofuran-5-yl)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1,2-oxazole-3-carboxamide

IUPAC name

5-(2-methyl-23-dihydro-1-benzofuran-5-yl)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-12-oxazole-3-carboxamide

SMILES

CC(C1)Oc(cc2)c1cc2-c1cc(C(Nc(cc2)ccc2S(Nc2nc(C)ccn2)(=O)=O)=O)no1

InChI

InChI=1S/C24H21N5O5S/c1-14-9-10-25-24(26-14)29-35(31,32)19-6-4-18(5-7-19)27-23(30)20-13-22(34-28-20)16-3-8-21-17(12-16)11-15(2)33-21/h3-10,12-13,15H,11H2,1-2H3,(H,27,30)(H,25,26,29)/t15-/m1/s1

InChI Key

YSGIQCBRNFPECO-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD12918269

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

491.53

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.504

Distribution Coefficient, logD

2.892

Water Solubility, LogSw

-3.86

Polar Surface Area

112.860

Acid Dissociation Constant (pKa)

6.91

Base Dissociation Constant (pKb)

-1.03

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.70

D337-1132 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D337-1132 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D337-1132?
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What is the minimum amount of D337-1132 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D337-1132
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D337-1132
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D337-1132 available by request