D337-1376 Screening compound: 5-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-[5-(propylsulfanyl)-1,3,4-thiadiazol-2-yl]-1,2-oxazole-3-carboxamide

D337-1376 Screening compound: 5-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-[5-(propylsulfanyl)-1,3,4-thiadiazol-2-yl]-1,2-oxazole-3-carboxamide
D337-1376 Screening compound: 5-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-[5-(propylsulfanyl)-1,3,4-thiadiazol-2-yl]-1,2-oxazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D337-1376
5-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-[5-(propylsulfanyl)-1,3,4-thiadiazol-2-yl]-1,2-oxazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D337-1376

Molecular Formula

C17H16N4O4S2 (C17 H16 N4 O4 S2)

Compound Name

5-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-[5-(propylsulfanyl)-1,3,4-thiadiazol-2-yl]-1,2-oxazole-3-carboxamide

IUPAC name

5-(23-dihydro-14-benzodioxin-6-yl)-N-[5-(propylsulfanyl)-134-thiadiazol-2-yl]-12-oxazole-3-carboxamide

SMILES

CCCSc1nnc(NC(c2noc(-c(cc3)cc4c3OCCO4)c2)=O)s1

InChI

InChI=1S/C17H16N4O4S2/c1-2-7-26-17-20-19-16(27-17)18-15(22)11-9-13(25-21-11)10-3-4-12-14(8-10)24-6-5-23-12/h3-4,8-9H,2,5-7H2,1H3,(H,18,19,22)

InChI Key

JYDNHJQSADEKGX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08546935

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.47

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.560

Distribution Coefficient, logD

3.556

Water Solubility, LogSw

-3.76

Polar Surface Area

83.594

Acid Dissociation Constant (pKa)

9.44

Base Dissociation Constant (pKb)

-4.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

D337-1376 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D337-1376 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D337-1376?
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What is the minimum amount of D337-1376 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D337-1376
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D337-1376
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D337-1376 available by request