D340-1837 Screening compound: 4-[4-(4-chlorophenyl)-4-hydroxypiperidine-1-carbonyl]-N-[(2-methoxyphenyl)methyl]-1H-imidazole-5-carboxamide

D340-1837 Screening compound: 4-[4-(4-chlorophenyl)-4-hydroxypiperidine-1-carbonyl]-N-[(2-methoxyphenyl)methyl]-1H-imidazole-5-carboxamide
D340-1837 Screening compound: 4-[4-(4-chlorophenyl)-4-hydroxypiperidine-1-carbonyl]-N-[(2-methoxyphenyl)methyl]-1H-imidazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D340-1837
4-[4-(4-chlorophenyl)-4-hydroxypiperidine-1-carbonyl]-N-[(2-methoxyphenyl)methyl]-1H-imidazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D340-1837

Molecular Formula

C24H25ClN4O4 (C24 H25 ClN4 O4)

Compound Name

4-[4-(4-chlorophenyl)-4-hydroxypiperidine-1-carbonyl]-N-[(2-methoxyphenyl)methyl]-1H-imidazole-5-carboxamide

IUPAC name

4-[4-(4-chlorophenyl)-4-hydroxypiperidine-1-carbonyl]-N-[(2-methoxyphenyl)methyl]-1H-imidazole-5-carboxamide

SMILES

COc1c(CNC(c2c(C(N(CC3)CCC3(c(cc3)ccc3Cl)O)=O)nc[nH]2)=O)cccc1

InChI

InChI=1S/C24H25ClN4O4/c1-33-19-5-3-2-4-16(19)14-26-22(30)20-21(28-15-27-20)23(31)29-12-10-24(32,11-13-29)17-6-8-18(25)9-7-17/h2-9,15,32H,10-14H2,1H3,(H,26,30)(H,27,28)

InChI Key

RKQOWSAUOOWPHT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14820621

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.94

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.434

Distribution Coefficient, logD

2.429

Water Solubility, LogSw

-3.11

Polar Surface Area

86.134

Acid Dissociation Constant (pKa)

7.53

Base Dissociation Constant (pKb)

0.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

D340-1837 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • PPI modulators
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with D340-1837 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D340-1837?
Check Price and Availability of D340-1837, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D340-1837 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D340-1837
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D340-1837
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D340-1837 available by request