D341-0451 Screening compound: 1-[5-(4-chlorophenyl)thieno[2,3-d]pyrimidin-4-yl]-4-ethylpiperazine

D341-0451 Screening compound: 1-[5-(4-chlorophenyl)thieno[2,3-d]pyrimidin-4-yl]-4-ethylpiperazine
D341-0451 Screening compound: 1-[5-(4-chlorophenyl)thieno[2,3-d]pyrimidin-4-yl]-4-ethylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound D341-0451
1-[5-(4-chlorophenyl)thieno[2,3-d]pyrimidin-4-yl]-4-ethylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D341-0451

Molecular Formula

C18H19ClN4S (C18 H19 ClN4 S)

Compound Name

1-[5-(4-chlorophenyl)thieno[2,3-d]pyrimidin-4-yl]-4-ethylpiperazine

IUPAC name

1-[5-(4-chlorophenyl)thieno[23-d]pyrimidin-4-yl]-4-ethylpiperazine

SMILES

CCN(CC1)CCN1c1c(c(-c(cc2)ccc2Cl)cs2)c2ncn1

InChI

InChI=1S/C18H19ClN4S/c1-2-22-7-9-23(10-8-22)17-16-15(11-24-18(16)21-12-20-17)13-3-5-14(19)6-4-13/h3-6,11-12H,2,7-10H2,1H3

InChI Key

SEOVLQZYRHFENU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02330269

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

358.89

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.654

Distribution Coefficient, logD

4.083

Water Solubility, LogSw

-4.93

Polar Surface Area

27.804

Acid Dissociation Constant (pKa)

22.35

Base Dissociation Constant (pKb)

7.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

D341-0451 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D341-0451 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D341-0451?
Check Price and Availability of D341-0451, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D341-0451 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D341-0451
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D341-0451
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D341-0451 available by request