D351-0127 Screening compound: 2-(4-methylphenyl)-5-[(4-phenylpiperazin-1-yl)methyl]-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one

D351-0127 Screening compound: 2-(4-methylphenyl)-5-[(4-phenylpiperazin-1-yl)methyl]-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
D351-0127 Screening compound: 2-(4-methylphenyl)-5-[(4-phenylpiperazin-1-yl)methyl]-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound D351-0127
2-(4-methylphenyl)-5-[(4-phenylpiperazin-1-yl)methyl]-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D351-0127

Molecular Formula

C23H24N6O (C23 H24 N6 O)

Compound Name

2-(4-methylphenyl)-5-[(4-phenylpiperazin-1-yl)methyl]-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one

IUPAC name

2-(4-methylphenyl)-5-[(4-phenylpiperazin-1-yl)methyl]-4H7H-[124]triazolo[15-a]pyrimidin-7-one

SMILES

Cc(cc1)ccc1-c(nc1NC(CN(CC2)CCN2c2ccccc2)=C2)nn1C2=O

InChI

InChI=1S/C23H24N6O/c1-17-7-9-18(10-8-17)22-25-23-24-19(15-21(30)29(23)26-22)16-27-11-13-28(14-12-27)20-5-3-2-4-6-20/h2-10,15H,11-14,16H2,1H3,(H,24,25,26)

InChI Key

BWIOJZCHZOPLNM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14822068

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.435

Distribution Coefficient, logD

3.142

Water Solubility, LogSw

-3.57

Polar Surface Area

58.333

Acid Dissociation Constant (pKa)

7.47

Base Dissociation Constant (pKb)

6.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

D351-0127 in Drug Discovery

Included in Screening Libraries

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with D351-0127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D351-0127?
Check Price and Availability of D351-0127, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D351-0127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D351-0127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D351-0127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D351-0127 available by request