D351-1065 Screening compound: N-(2-fluorophenyl)-2-(2-{4-[(4-methoxyphenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)acetamide

D351-1065 Screening compound: N-(2-fluorophenyl)-2-(2-{4-[(4-methoxyphenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)acetamide
D351-1065 Screening compound: N-(2-fluorophenyl)-2-(2-{4-[(4-methoxyphenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D351-1065
N-(2-fluorophenyl)-2-(2-{4-[(4-methoxyphenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D351-1065

Molecular Formula

C24H23FN4O2S (C24 H23 FN4 O2 S)

Compound Name

N-(2-fluorophenyl)-2-(2-{4-[(4-methoxyphenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)acetamide

IUPAC name

N-(2-fluorophenyl)-2-(2-{4-[(4-methoxyphenyl)methyl]-35-dimethyl-1H-pyrazol-1-yl}-13-thiazol-4-yl)acetamide

SMILES

Cc1c(Cc(cc2)ccc2OC)c(C)nn1-c1nc(CC(Nc(cccc2)c2F)=O)cs1

InChI

InChI=1S/C24H23FN4O2S/c1-15-20(12-17-8-10-19(31-3)11-9-17)16(2)29(28-15)24-26-18(14-32-24)13-23(30)27-22-7-5-4-6-21(22)25/h4-11,14H,12-13H2,1-3H3,(H,27,30)

InChI Key

XUSWSBWOPZFRQX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14822294

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.702

Distribution Coefficient, logD

4.701

Water Solubility, LogSw

-4.48

Polar Surface Area

54.424

Acid Dissociation Constant (pKa)

10.65

Base Dissociation Constant (pKb)

3.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

D351-1065 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with D351-1065 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D351-1065?
Check Price and Availability of D351-1065, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D351-1065 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D351-1065
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D351-1065
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D351-1065 available by request