D351-1219 Screening compound: 2-{2-[3,5-dimethyl-4-(3-methylbutyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}-N-(2,3-dimethylphenyl)acetamide

D351-1219 Screening compound: 2-{2-[3,5-dimethyl-4-(3-methylbutyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}-N-(2,3-dimethylphenyl)acetamide
D351-1219 Screening compound: 2-{2-[3,5-dimethyl-4-(3-methylbutyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}-N-(2,3-dimethylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D351-1219
2-{2-[3,5-dimethyl-4-(3-methylbutyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}-N-(2,3-dimethylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D351-1219

Molecular Formula

C23H30N4OS (C23 H30 N4 OS)

Compound Name

2-{2-[3,5-dimethyl-4-(3-methylbutyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}-N-(2,3-dimethylphenyl)acetamide

IUPAC name

2-{2-[35-dimethyl-4-(3-methylbutyl)-1H-pyrazol-1-yl]-13-thiazol-4-yl}-N-(23-dimethylphenyl)acetamide

SMILES

CC(C)CCc1c(C)n(-c2nc(CC(Nc3c(C)c(C)ccc3)=O)cs2)nc1C

InChI

InChI=1S/C23H30N4OS/c1-14(2)10-11-20-17(5)26-27(18(20)6)23-24-19(13-29-23)12-22(28)25-21-9-7-8-15(3)16(21)4/h7-9,13-14H,10-12H2,1-6H3,(H,25,28)

InChI Key

SCKARGWUQNGJGJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14822318

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.58

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.686

Distribution Coefficient, logD

5.686

Water Solubility, LogSw

-5.40

Polar Surface Area

47.152

Acid Dissociation Constant (pKa)

12.48

Base Dissociation Constant (pKb)

3.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

D351-1219 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system

References: we are preparing a list of scientific research reports with D351-1219 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D351-1219?
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What is the minimum amount of D351-1219 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D351-1219
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D351-1219
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D351-1219 available by request