D354-0124 Screening compound: 2-methylpropyl 2-[5-(3-fluoro-4-methylphenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate

D354-0124 Screening compound: 2-methylpropyl 2-[5-(3-fluoro-4-methylphenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate
D354-0124 Screening compound: 2-methylpropyl 2-[5-(3-fluoro-4-methylphenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound D354-0124
2-methylpropyl 2-[5-(3-fluoro-4-methylphenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D354-0124

Molecular Formula

C20H20FN3O4S (C20 H20 FN3 O4 S)

Compound Name

2-methylpropyl 2-[5-(3-fluoro-4-methylphenyl)-1,2-oxazole-3-amido]-4-methyl-1,3-thiazole-5-carboxylate

IUPAC name

2-methylpropyl 2-[5-(3-fluoro-4-methylphenyl)-12-oxazole-3-amido]-4-methyl-13-thiazole-5-carboxylate

SMILES

CC(C)COC(c1c(C)nc(NC(c2noc(-c3cc(F)c(C)cc3)c2)=O)s1)=O

InChI

InChI=1S/C20H20FN3O4S/c1-10(2)9-27-19(26)17-12(4)22-20(29-17)23-18(25)15-8-16(28-24-15)13-6-5-11(3)14(21)7-13/h5-8,10H,9H2,1-4H3,(H,22,23,25)

InChI Key

UBYTYABPSRXJID-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08544873

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.379

Distribution Coefficient, logD

5.306

Water Solubility, LogSw

-5.46

Polar Surface Area

76.617

Acid Dissociation Constant (pKa)

8.14

Base Dissociation Constant (pKb)

-0.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

D354-0124 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with D354-0124 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D354-0124?
Check Price and Availability of D354-0124, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D354-0124 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D354-0124
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D354-0124
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D354-0124 available by request