D356-2444 Screening compound: N-[2-(cyclohexylcarbamoyl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

D356-2444 Screening compound: N-[2-(cyclohexylcarbamoyl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide
D356-2444 Screening compound: N-[2-(cyclohexylcarbamoyl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D356-2444
N-[2-(cyclohexylcarbamoyl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D356-2444

Molecular Formula

C23H29N3O4S2 (C23 H29 N3 O4 S2)

Compound Name

N-[2-(cyclohexylcarbamoyl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

IUPAC name

N-[2-(cyclohexylcarbamoyl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1S(c1cccs1)(=O)=O)Nc(cccc1)c1C(NC1CCCCC1)=O

InChI

InChI=1S/C23H29N3O4S2/c27-22(17-8-6-14-26(16-17)32(29,30)21-13-7-15-31-21)25-20-12-5-4-11-19(20)23(28)24-18-9-2-1-3-10-18/h4-5,7,11-13,15,17-18H,1-3,6,8-10,14,16H2,(H,24,28)(H,25,27)/t17-/m0/s1

InChI Key

HTYRGWSPNGORAP-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD14824165

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.63

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.436

Distribution Coefficient, logD

3.427

Water Solubility, LogSw

-3.84

Polar Surface Area

79.433

Acid Dissociation Constant (pKa)

9.08

Base Dissociation Constant (pKb)

-1.73

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

47.80

D356-2444 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GABA Library (7115 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • GPCR
  • Ion Channels
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with D356-2444 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D356-2444?
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What is the minimum amount of D356-2444 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D356-2444
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D356-2444
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D356-2444 available by request