D356-2514 Screening compound: N-(2-{[(pyridin-3-yl)methyl]carbamoyl}phenyl)-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

D356-2514 Screening compound: N-(2-{[(pyridin-3-yl)methyl]carbamoyl}phenyl)-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide
D356-2514 Screening compound: N-(2-{[(pyridin-3-yl)methyl]carbamoyl}phenyl)-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D356-2514
N-(2-{[(pyridin-3-yl)methyl]carbamoyl}phenyl)-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D356-2514

Molecular Formula

C23H24N4O4S2 (C23 H24 N4 O4 S2)

Compound Name

N-(2-{[(pyridin-3-yl)methyl]carbamoyl}phenyl)-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

IUPAC name

N-(2-{[(pyridin-3-yl)methyl]carbamoyl}phenyl)-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1S(c1cccs1)(=O)=O)Nc(cccc1)c1C(NCc1cnccc1)=O

InChI

InChI=1S/C23H24N4O4S2/c28-22(18-7-4-12-27(16-18)33(30,31)21-10-5-13-32-21)26-20-9-2-1-8-19(20)23(29)25-15-17-6-3-11-24-14-17/h1-3,5-6,8-11,13-14,18H,4,7,12,15-16H2,(H,25,29)(H,26,28)/t18-/m0/s1

InChI Key

OEILQLTZVUJUJR-SFHVURJKSA-N

MDL Number (MFCD)

MFCD14824198

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.6

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.865

Distribution Coefficient, logD

1.860

Water Solubility, LogSw

-2.31

Polar Surface Area

89.226

Acid Dissociation Constant (pKa)

9.34

Base Dissociation Constant (pKb)

3.76

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.10

D356-2514 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

New Agro Library (44492 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Others
  • Kinases
  • Phosphatases
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with D356-2514 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D356-2514?
Check Price and Availability of D356-2514, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D356-2514 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D356-2514
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D356-2514
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D356-2514 available by request