D356-2524 Screening compound: N-[4-chloro-2-(trifluoromethyl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

D356-2524 Screening compound: N-[4-chloro-2-(trifluoromethyl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide
D356-2524 Screening compound: N-[4-chloro-2-(trifluoromethyl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D356-2524
N-[4-chloro-2-(trifluoromethyl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D356-2524

Molecular Formula

C17H16ClF3N2O3S2 (C17 H16 ClF3 N2 O3 S2)

Compound Name

N-[4-chloro-2-(trifluoromethyl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

IUPAC name

N-[4-chloro-2-(trifluoromethyl)phenyl]-1-(thiophene-2-sulfonyl)piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1S(c1cccs1)(=O)=O)Nc(cc1)c(C(F)(F)F)cc1Cl

InChI

InChI=1S/C17H16ClF3N2O3S2/c18-12-5-6-14(13(9-12)17(19,20)21)22-16(24)11-3-1-7-23(10-11)28(25,26)15-4-2-8-27-15/h2,4-6,8-9,11H,1,3,7,10H2,(H,22,24)/t11-/m0/s1

InChI Key

IWPQKZPNEOFXCM-NSHDSACASA-N

MDL Number (MFCD)

MFCD14824203

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.91

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.872

Distribution Coefficient, logD

3.868

Water Solubility, LogSw

-4.41

Polar Surface Area

55.295

Acid Dissociation Constant (pKa)

9.42

Base Dissociation Constant (pKb)

-2.27

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

35.30

D356-2524 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D356-2524 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D356-2524?
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What is the minimum amount of D356-2524 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D356-2524
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D356-2524
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D356-2524 available by request