D357-0525 Screening compound: N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-2-(3-methylphenoxy)acetamide

D357-0525 Screening compound: N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-2-(3-methylphenoxy)acetamide
D357-0525 Screening compound: N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-2-(3-methylphenoxy)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D357-0525
N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-2-(3-methylphenoxy)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D357-0525

Molecular Formula

C21H27ClN2O2 (C21 H27 ClN2 O2)

Compound Name

N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-2-(3-methylphenoxy)acetamide

IUPAC name

N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-2-(3-methylphenoxy)acetamide

SMILES

CCN(CC)C(CNC(COc1cc(C)ccc1)=O)c(cccc1)c1Cl

InChI

InChI=1S/C21H27ClN2O2/c1-4-24(5-2)20(18-11-6-7-12-19(18)22)14-23-21(25)15-26-17-10-8-9-16(3)13-17/h6-13,20H,4-5,14-15H2,1-3H3,(H,23,25)/t20-/m0/s1

InChI Key

SQIQAYXAOKGZLS-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD12915247

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.91

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.106

Distribution Coefficient, logD

3.697

Water Solubility, LogSw

-4.31

Polar Surface Area

34.211

Acid Dissociation Constant (pKa)

13.20

Base Dissociation Constant (pKb)

7.59

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

D357-0525 in Drug Discovery

Included in Screening Libraries

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with D357-0525 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D357-0525?
Check Price and Availability of D357-0525, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D357-0525 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D357-0525
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D357-0525
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D357-0525 available by request