D357-0532 Screening compound: N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-4-(propan-2-yloxy)benzamide

D357-0532 Screening compound: N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-4-(propan-2-yloxy)benzamide
D357-0532 Screening compound: N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-4-(propan-2-yloxy)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D357-0532
N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-4-(propan-2-yloxy)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D357-0532

Molecular Formula

C22H29ClN2O2 (C22 H29 ClN2 O2)

Compound Name

N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-4-(propan-2-yloxy)benzamide

IUPAC name

N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-4-(propan-2-yloxy)benzamide

SMILES

CCN(CC)C(CNC(c(cc1)ccc1OC(C)C)=O)c(cccc1)c1Cl

InChI

InChI=1S/C22H29ClN2O2/c1-5-25(6-2)21(19-9-7-8-10-20(19)23)15-24-22(26)17-11-13-18(14-12-17)27-16(3)4/h7-14,16,21H,5-6,15H2,1-4H3,(H,24,26)/t21-/m0/s1

InChI Key

GPTFPEOBTNTBFD-NRFANRHFSA-N

MDL Number (MFCD)

MFCD12914384

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.94

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.485

Distribution Coefficient, logD

4.388

Water Solubility, LogSw

-4.48

Polar Surface Area

33.727

Acid Dissociation Constant (pKa)

12.05

Base Dissociation Constant (pKb)

6.80

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.90

D357-0532 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
  • Ion Channels

References: we are preparing a list of scientific research reports with D357-0532 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D357-0532?
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What is the minimum amount of D357-0532 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D357-0532
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D357-0532
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D357-0532 available by request