D357-0553 Screening compound: N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-2-fluorobenzamide

D357-0553 Screening compound: N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-2-fluorobenzamide
D357-0553 Screening compound: N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-2-fluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D357-0553
N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-2-fluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D357-0553

Molecular Formula

C19H22ClFN2O (C19 H22 ClFN2 O)

Compound Name

N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-2-fluorobenzamide

IUPAC name

N-[2-(2-chlorophenyl)-2-(diethylamino)ethyl]-2-fluorobenzamide

SMILES

CCN(CC)C(CNC(c(cccc1)c1F)=O)c(cccc1)c1Cl

InChI

InChI=1S/C19H22ClFN2O/c1-3-23(4-2)18(14-9-5-7-11-16(14)20)13-22-19(24)15-10-6-8-12-17(15)21/h5-12,18H,3-4,13H2,1-2H3,(H,22,24)/t18-/m0/s1

InChI Key

JMXYKWIAVXMPQD-SFHVURJKSA-N

MDL Number (MFCD)

MFCD08547239

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

348.85

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.099

Distribution Coefficient, logD

4.002

Water Solubility, LogSw

-4.51

Polar Surface Area

26.925

Acid Dissociation Constant (pKa)

10.81

Base Dissociation Constant (pKb)

6.80

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.60

D357-0553 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

CNS BBB Library (22607 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
  • Nervous system
Mechanism of action:
  • Epigenetic
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with D357-0553 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D357-0553?
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What is the minimum amount of D357-0553 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D357-0553
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D357-0553
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D357-0553 available by request