D364-0029 Screening compound: 6-hydroxy-5-[5-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

D364-0029 Screening compound: 6-hydroxy-5-[5-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
D364-0029 Screening compound: 6-hydroxy-5-[5-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D364-0029
6-hydroxy-5-[5-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D364-0029

Molecular Formula

C15H16N4O4 (C15 H16 N4 O4)

Compound Name

6-hydroxy-5-[5-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

6-hydroxy-5-[5-(4-hydroxyphenyl)-45-dihydro-1H-pyrazol-3-yl]-13-dimethyl-1234-tetrahydropyrimidine-24-dione

SMILES

CN(C(C(C(C1)=NNC1c(cc1)ccc1O)=C(N1C)O)=O)C1=O

InChI

InChI=1S/C15H16N4O4/c1-18-13(21)12(14(22)19(2)15(18)23)11-7-10(16-17-11)8-3-5-9(20)6-4-8/h3-6,10,16,20-21H,7H2,1-2H3/t10-/m1/s1

InChI Key

ZVPRVEYHKDJPAY-SNVBAGLBSA-N

MDL Number (MFCD)

MFCD27581911

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

316.32

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.708

Distribution Coefficient, logD

-3.731

Water Solubility, LogSw

-1.65

Polar Surface Area

90.150

Acid Dissociation Constant (pKa)

2.96

Base Dissociation Constant (pKb)

0.29

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.70

D364-0029 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D364-0029 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D364-0029?
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What is the minimum amount of D364-0029 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D364-0029
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D364-0029
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D364-0029 available by request